• Corpus ID: 53963985

Magnesium Sulphate for management of Eclampsia in low income countries

  title={Magnesium Sulphate for management of Eclampsia in low income countries},
  author={Rosemary Ogu and Zainab Bello and L. O. Omo-Aghoja and Emily A. Nzeribe and P. A. Feyi-waboso and Friday E. Okonofua},
important cause of maternal mortality in low income countries. Worldwide, an estimated half a million women die each year from various complications of pregnancy. Of these, 50,000 women (nearly 10% of maternal deaths) die annually following eclamptic convulsions, with 99% of these deaths occurring in low and middle income countries. Eclampsia is usually a consequence of pre-existing pre-eclampsia, a multisystemic disease associated with raised blood pressure and proteinuria. Primary prevention… 
A shortened versus standard matched postpartum magnesium sulphate regimen in the treatment of eclampsia: a randomised controlled trial.
The shortened postpartum course of magnesium sulphate is as effective as the standard Pritchard regimen in the management of eclampsia.
Training health workers for magnesium sulfate use reduces case fatality from eclampsia: results from a multicenter trial
To investigate the effectiveness of an intervention aimed at improving the case management of eclampsia, a large number of women were referred for treatment with or without pregnancy-related complications.


Magnesium sulphate and other anticonvulsants for women with pre-eclampsia.
Magnesium sulphate more than halves the risk of eclampsia, and probably reduces therisk of maternal death, and does not improve outcome for the baby, in the short term.
Is serum magnesium estimate necessary in patients with eclampsia on magnesium sulphate?
Serum magnesium levels in eclamptic patients treated with magnesium sulphate were within the therapeutic range, therefore, routine estimation of this cation is not necessary and it is suggested that serum estimation be limited to cases where clinical monitors suggest toxicity.
Translating research into policy and practice in developing countries: a case study of magnesium sulphate for pre-eclampsia
The policy changes needed to ensure widespread availability and use of magnesium sulphate are variable and complex, and it makes it difficult to envisage any single intervention strategy that might be used to promote the uptake of research findings on research findings into policy across the study settings.
Cost‐effectiveness of prophylactic magnesium sulphate for 9996 women with pre‐eclampsia from 33 countries: economic evaluation of the Magpie Trial
  • J. Simon, A. Gray, L. Duley
  • Medicine, Political Science
    BJOG : an international journal of obstetrics and gynaecology
  • 2006
To assess the cost‐effectiveness of using magnesium sulphate for pre‐eclampsia to prevent eClampsia, a large number of studies have used it for this purpose.
Maternal mortality associated with hypertensive disorders of pregnancy in Africa, Asia, Latin America and the Caribbean
  • L. Duley
  • Political Science, Medicine
    British journal of obstetrics and gynaecology
  • 1992
Estimates of maternal mortality associated with hypertensive disorders of pregnancy in Africa, Asia, Latin America and the Caribbean are presented and strategies to prevent these deaths are discussed.