Magnesium: A New Therapy for Idiopathic Sudden Sensorineural Hearing Loss

@article{Gordin2002MagnesiumAN,
  title={Magnesium: A New Therapy for Idiopathic Sudden Sensorineural Hearing Loss},
  author={Ariel Gordin and David M. Goldenberg and Avishay Golz and Aviram Netzer and Henry Zvi Joachims},
  journal={Otology \& Neurotology},
  year={2002},
  volume={23},
  pages={447-451}
}
Objective To determine whether treatment with Mg2+ improves the outcome of idiopathic sudden hearing loss and to investigate which variables influence its prognosis. Study Design Prospective randomized study. Setting Department of Otolaryngology–Head and Neck Surgery, Rambam Medical Center, Haifa, Israel. Patients The study group included 133 patients. Sixty patients were treated with carbogen inhalation, and 73 were treated with a combination of carbogen inhalation and intravenous MgSO4… 
Efficacy of Hyperbaric Oxygen on Idiopathic Sudden Sensorineural Hearing Loss and Its Correlation with Treatment Course: Prospective Clinical Research
TLDR
HBOT + IVS is an effective method for ISSNHL, especially for the recovery of low-frequency hearing and initial hearing levels of severe and profound, and prolonging the course of HBOT did not significantly improve it.
Effectiveness of hyperbaric oxygen therapy in idiopathic sudden hearing loss
TLDR
This study did not reveal a trend in favour of HBO therapy and inter- or intra-group comparison of age stratification did not produce significant differences in PTA and in the number of patients who experienced hearing gain.
Prognostic effect of hyperbaric oxygen therapy starting time for sudden sensorineural hearing loss
TLDR
Starting hyperbaric oxygen therapy in patients with sudden sensorineural hearing loss within the first 14 days has positive effect on the prognosis of the disease.
Effectiveness of oral zinc supplementation in the treatment of idiopathic sudden sensorineural hearing loss (ISSNHL).
TLDR
Zinc supplementation does not have benefit when combined with standard treatment, and more subjects and well-designed studies are needed to verify the effect of zinc.
Intratympanic Versus Oral Steroids in the Mangement of Idiopathic Sudden Sensorineural Hearing Loss
TLDR
The efficacy of intratympanic steroid and oral steroid in the improvement of hearing in patients with idiopathic sudden sensorineural hearing loss (ISSHL) was compared to the PTA taken on the 7 th day, 14th day, and 30 th day after treatment.
Antioxidants in Treatment of Idiopathic Sudden Hearing Loss
TLDR
Patients treated with the addition of vitamin E achieved better recovery than did the control patients and further studies should be directed toward a better understanding of the role of antioxidants in idiopathic sudden hearing loss.
Clinical, etiological and progression factors of hearing in sudden deafness.
Magnesium Treatment for Sudden Hearing Loss
TLDR
Magnesium is a relatively safe and convenient adjunct to steroid treatment for enhancing the improvement in hearing, especially in the low-tone range, in patients with sudden sensorineural hearing loss.
EVALUATION OF TREATMENT RESULTS APPLIED IN SUDDEN HEARING LOSSES TREATED IN OUR CLINIC
TLDR
Early treatment and low degrees of SSNHL severity are positive prognostic factors and there was no significant differences between tinnitus and vertigo and SSN NHL relationship.
Therapeutic Effects of Zinc on Patients Who Have Sudden Sensorineural Hearing Loss with Normal Serum Zinc Level
TLDR
Whether treatment with zinc can improve the outcome of sudden sensorineural hearing loss (SSNHL) andral zinc supplementation may have beneficial effects in the treatment of SSNHL is investigated.
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References

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Management of idiopathic sudden sensorineural hearing loss.
Objective: To determine if any consensus exists regarding the efficacy of treatment in idiopathic sudden sensorineural hearing loss syndrome (ISSNHL). Data Sources: A review of the literature from
Management of idiopathic sudden sensorineural hearing loss.
OBJECTIVE To determine if any consensus exists regarding the efficacy of treatment in idiopathic sudden sensorineural hearing loss syndrome (ISSNHL). DATA SOURCES A review of the literature from
Evaluation of a “Shotgun” Regimen for Sudden Hearing Loss
  • S. A. Wilkins, D. Mattox, A. Lyles
  • Medicine
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • 1987
TLDR
The results suggest that this “shotgun” approach for treatment of sudden hearing loss offers no better outcome than is reported in the literature for spontaneous recovery.
The efficacy of steroids in the treatment of idiopathic sudden hearing loss. A double-blind clinical study.
TLDR
The nature of the hearing loss and its susceptibility to improvement with steroid therapy lend support to the hypothesis that viral cochlitis is the primary cause of idiopathic sudden hearing loss.
Natural History of Sudden Sensorineural Hearing Loss
TLDR
It is found that 65% recover completely to functional hearing levels spontaneously and independent of any type of medical treatment, and that because of the high spontaneous recovery rates, tympanotomies seeking perilymph fistulas should be delayed ten days unless there is a progressive hearing loss.
Sudden hearing loss: Eight years' experience and suggested prognostic table
  • F. Byl
  • Medicine
    The Laryngoscope
  • 1984
TLDR
In an 8‐year prospective study of 225 SHL patients, overall, normal, or complete recovery occurred in 45% of patients and late otologic complications in 28%.
Seventy‐six cases of presumed sudden hearing loss occurring in 1973: Prognosis and incidence
  • F. Byl
  • Medicine
    The Laryngoscope
  • 1977
A sudden hearing loss (SHL) research clinic to which 30 members of an ENT Society refer patients, accumulates information about incidence, prognosis, recovery patterns, and treatment of SHL. The
Idiopathic sudden hearing loss.
TLDR
The absence of vertigo at th clinical onset and low tone hearing loss are associated with better hearing recovery, and treatments proposed include close observation for spontaneous recovery, steroid theray, and combination regimens of vasodilators, steroids, diuretics, and intravenous iodinated radiocontrast material.
Outcome of sudden deafness with and without vertigo
TLDR
Hearing recovery of high‐tone frequencies was worse in patients with vertigo than in those without vertigo even when the initial hearing loss was the same, and it is hypothesized that these results can be explained by anatomical factors; the cochlear basal turn being more proximal to the vestibular apparatus than the upper turn.
Sudden idiopathic sensori-neural hearing loss: some observations.
TLDR
In general, prognosis for recovery from sudden hearing loss correlates best with the interval between symptom onset and the first audiogram, and very poorly with either the type of treatment or the intervals between symptoms and the patient's first visit to a physician.
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