Mads and Smads in TGF beta signalling.

@article{Attisano1998MadsAS,
  title={Mads and Smads in TGF beta signalling.},
  author={Liliana Attisano and Jeff L. Wrana},
  journal={Current opinion in cell biology},
  year={1998},
  volume={10 2},
  pages={188-94}
}
The discovery of the Mothers against dpp (Mad) gene in Drosophila has opened a window on an entirely unique signalling pathway that functions to mediate responses to the tumour growth factor beta (TGF beta) superfamily. This pathway, which is comprised of a family of proteins related to Mad, acts to convey signals directly from TGF beta receptors to the nucleus and is implicated in the pathogenesis of human diseases. 

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 56 extracted citations

Similar Papers

Loading similar papers…