Macular pigment lutein is antiinflammatory in preventing choroidal neovascularization.

  title={Macular pigment lutein is antiinflammatory in preventing choroidal neovascularization.},
  author={Kanako Izumi-Nagai and Norihiro Nagai and Kazuhiro Ohgami and Shingo Satofuka and Yoko Ozawa and Kazuo Tsubota and Kazuo Umezawa and Shigeaki Ohno and Yuichi Oike and Susumu Ishida},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  volume={27 12},
BACKGROUND Choroidal neovascularization (CNV) is a critical pathogenesis in age-related macular degeneration, the most common cause of blindness in the developed countries. The aim of the current study was to investigate the effect of lutein supplementation on the development of the murine model of laser-induced CNV together with underlying molecular mechanisms. METHODS AND RESULTS Mice were orally pretreated with lutein daily from 3 days before laser photocoagulation until the end of the… CONTINUE READING
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