Macular corneal dystrophy: the macromolecular structure of the stroma observed using electron microscopy and synchrotron X-ray diffraction.

@article{Meek1989MacularCD,
  title={Macular corneal dystrophy: the macromolecular structure of the stroma observed using electron microscopy and synchrotron X-ray diffraction.},
  author={Keith M. Meek and Andrew J Quantock and Gerald F. Elliott and Alex Ridgway and Andrew B Tullo and A. J. Bron and Eugene J.-M.A. Thonar},
  journal={Experimental eye research},
  year={1989},
  volume={49 6},
  pages={941-58}
}
The distribution of sulphated proteoglycans within the stromas of three patients (A,B,C) suffering from macular corneal dystrophy was studied using the specific dye Cuprolinic Blue in a 'critical electrolyte concentration' method. The corneas were examined using transmission electron microscopy and A and C were further studied by low-angle synchroton X-ray diffraction. Sera from all three patients were analyzed for the presence of keratan sulphate using a monoclonal antibody in an enzyme-linked… CONTINUE READING
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