Macula densa stimulation of renin is reversed by selective inhibition of neuronal nitric oxide synthase.

Abstract

The neuronal isoform of nitric oxide synthase (nNOS) exists in the renal cortex predominantly in the macula densa, suggesting that nitric oxide (NO) derived from the macula densa plays a role in feedback regulation of renin in response to altered sodium metabolism. To determine if nNOS is a critical component in renin stimulation induced by dietary sodium… (More)

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Cite this paper

@article{Beierwaltes1997MaculaDS, title={Macula densa stimulation of renin is reversed by selective inhibition of neuronal nitric oxide synthase.}, author={William H. Beierwaltes}, journal={The American journal of physiology}, year={1997}, volume={272 5 Pt 2}, pages={R1359-64} }