# Macroscopic loop formation in circular DNA denaturation.

@article{Kabakolu2012MacroscopicLF,
title={Macroscopic loop formation in circular DNA denaturation.},
author={Alkan Kabakçıoğlu and Amir Bar and David Mukamel},
journal={Physical review. E, Statistical, nonlinear, and soft matter physics},
year={2012},
volume={85 5 Pt 1},
pages={
051919
}
}
• Published 1 April 2012
• Physics, Biology, Medicine
• Physical review. E, Statistical, nonlinear, and soft matter physics
The statistical mechanics of DNA denaturation under fixed linking number is qualitatively different from that of unconstrained DNA. Quantitatively different melting scenarios are reached from two alternative assumptions, namely, that the denatured loops are formed at the expense of (i) overtwist or (ii) supercoils. Recent work has shown that the supercoiling mechanism results in a picture similar to Bose-Einstein condensation where a macroscopic loop appears at T{c} and grows steadily with…
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