Macroscopic anisotropic bone material properties in children with severe osteogenesis imperfecta.


Children with severe osteogenesis imperfecta (OI) typically experience numerous fractures and progressive skeletal deformities over their lifetime. Recent studies proposed finite element models to assess fracture risk and guide clinicians in determining appropriate intervention in children with OI, but lack of appropriate material property inputs remains a… (More)
DOI: 10.1016/j.jbiomech.2017.09.003