Macroporous monolithic layers as efficient 3-D microarrays for quantitative detection of virus-like particles.

@article{Kalashnikova2007MacroporousML,
  title={Macroporous monolithic layers as efficient 3-D microarrays for quantitative detection of virus-like particles.},
  author={Irina Kalashnikova and Natalia O. Ivanova and Tatiana B Tennikova},
  journal={Analytical chemistry},
  year={2007},
  volume={79 14},
  pages={
          5173-80
        }
}
The main objective of the present paper was to test the recently developed new type of 3-D protein microarray system based on glycidyl methacrylate-co-ethylene glycol dimethacrylate (GMA-EDMA) monolithic material for efficient and fast virus detection. The large-size synthetic particles bearing adsorption-responsible biomolecules on their surface were used as a virus model. Two affinity pairs were chosen for present study. Model virus-like particles, close to the dimensions of human viruses… CONTINUE READING