Macrophages related to Bruch's membrane in age-related macular degeneration.

  title={Macrophages related to Bruch's membrane in age-related macular degeneration.},
  author={Murray C. Killingsworth and John Sarks and Shirley Sarks},
  volume={4 ( Pt 4)},
This report describes focal thinning of Bruch's membrane in age-related macular degeneration and suggests a role for macrophages in this process. Electron microscopy was performed on four eyes ranging from normal ageing to age-related macular degeneration with early subretinal neovascularisation. As degeneration progressed multiple segments of thinning of Bruch's membrane were observed and macrophages appeared to engulf fragments of the outer collagenous zone. An associated finding at this… CONTINUE READING


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