Macrophages in the embryo and beyond: Much more than just giant phagocytes

  title={Macrophages in the embryo and beyond: Much more than just giant phagocytes},
  author={D. Ovchinnikov},
  • D. Ovchinnikov
  • Published 2008
  • Biology, Medicine
  • genesis
  • Originally recognized as an essential part of the innate and acquired immune systems, macrophages emerged as omnipresent and influential regulators of embryo‐ and organo‐genesis, as well as of tissue and tumor growth. Macrophages are present essentially in all tissues, beginning with embryonic development and, in addition to their role in host defense and in the clearance of apoptotic cells, are being increasingly recognized for their trophic function and role in regeneration. Some tissue… CONTINUE READING
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