Macrophages in spinal cord injury: phenotypic and functional change from exposure to myelin debris.

@article{Wang2015MacrophagesIS,
  title={Macrophages in spinal cord injury: phenotypic and functional change from exposure to myelin debris.},
  author={Xi Wang and Kai Cao and Xin Yu Sun and Yongxiong Chen and Zhaoxia Duan and Li Sun and Lei Guo and Paul Bai and Dongming Sun and Jianqing Fan and Xijing He and Wise Young and Yi Ren},
  journal={Glia},
  year={2015},
  volume={63 4},
  pages={635-51}
}
Macrophage activation and persistent inflammation contribute to the pathological process of spinal cord injury (SCI). It was reported that M2 macrophages were induced at 3-7 days after SCI but M2 markers were reduced or eliminated after 1 week. By contrast, M1 macrophage response is rapidly induced and then maintained at injured spinal cord. However, factors that modulate macrophage phenotype and function are poorly understood. We developed a model to distinguish bone-marrow derived macrophages… CONTINUE READING
Highly Cited
This paper has 98 citations. REVIEW CITATIONS
Recent Discussions
This paper has been referenced on Twitter 4 times over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 24 extracted citations

98 Citations

02040602015201620172018
Citations per Year
Semantic Scholar estimates that this publication has 98 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
Showing 1-10 of 72 references

Myelinderived lipids modulate macrophage activity by liver X receptor activation

  • JFJ Bogie, S Timmermans, +8 authors JJ. Hendriks
  • Plos One 7.
  • 2012
Highly Influential
4 Excerpts

Similar Papers

Loading similar papers…