Macrophages in cancer metastases and their relevance to metastatic growth

  title={Macrophages in cancer metastases and their relevance to metastatic growth},
  author={Marc E. Key},
  journal={Cancer and Metastasis Reviews},
The dissemination of malignant cells throughout the body to form secondary growths is a highly complex process dependent upon both host and tumor cell properties. One potential defensive system which could influence the outcome of metastasis is the mononuclear phagocyte system. Although macrophages have been observed in essentially all primary and metastatic tumors examined regardless of histologic type or anatomic location, the biological significance of these observations is far from clear… CONTINUE READING

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