Macrophages behaving badly: infected cells and subversion of immune responses to Theileria annulata.

@article{Campbel1999MacrophagesBB,
  title={Macrophages behaving badly: infected cells and subversion of immune responses to Theileria annulata.},
  author={J D Campbel and Roger L. Spooner},
  journal={Parasitology today},
  year={1999},
  volume={15 1},
  pages={10-6}
}
The protozoan parasite Theileria annulata is the causative agent of the tick-borne disease tropical theileriosis, responsible for morbidity and mortality of cattle in many developing countries. Here, John Campbell and Roger Spooner discuss how the parasite might evade immune destruction during an acute primary infection. Theileria annulata macroschizont-infected macrophages act as over-efficient antigen-presenting cells within the infected draining lymph node. Infected cells activate CD4+ and… CONTINUE READING

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