Macrophages as susceptible targets for HIV infection, persistent viral reservoirs in tissue, and key immunoregulatory cells that control levels of virus replication and extent of disease.

Abstract

Although macrophages are major targets for human immunodeficiency virus (HIV) infection in vivo, study of HIV-macrophage interactions in vitro was hindered because many laboratory strains of HIV would not replicate in macrophages, and because survival of macrophages in culture was poor. Addition of purified macrophage colony-stimulating factor (M-CSF) to… (More)

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@article{Meltzer1990MacrophagesAS, title={Macrophages as susceptible targets for HIV infection, persistent viral reservoirs in tissue, and key immunoregulatory cells that control levels of virus replication and extent of disease.}, author={Micah Meltzer and M. Nakamura and Bryan Hansen and Jim A. Turpin and Debra Chester Kalter and Howard E. Gendelman}, journal={AIDS research and human retroviruses}, year={1990}, volume={6 8}, pages={967-71} }