Macrophages Influence Vessel Formation in 3D Bioactive Hydrogels

@article{Moore2017MacrophagesIV,
  title={Macrophages Influence Vessel Formation in 3D Bioactive Hydrogels},
  author={Erika M Moore and Grace Ying and Jennifer L. West},
  journal={Advanced Biosystems},
  year={2017},
  volume={1}
}
Macrophages may play a beneficial role in blood vessel development. To study the role of macrophages in vessel development for regenerative medicine, a bioactive poly(ethylene glycol)‐based hydrogel scaffold that is modified for integrin‐mediated cell adhesion and biodegradation by matrix‐metalloproteinases 2 and 9 is utilized. This scaffold serves as a tunable cell microenvironment and supports the formation of microvascular networks. When encapsulated with endothelial cells, macrophages… 
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