Macrophages: A review of their role in wound healing and their therapeutic use.

@article{Snyder2016MacrophagesAR,
  title={Macrophages: A review of their role in wound healing and their therapeutic use.},
  author={Robert Jay Snyder and John C. Lantis and Robert Scott Kirsner and Vivek M Shah and Michael Molyneaux and Marissa Janine Carter},
  journal={Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society},
  year={2016},
  volume={24 4},
  pages={613-29}
}
Macrophages are mononuclear phagocytes established during embryogenesis and derived from the yolk sac or the fetal liver but also recruited from the blood and bone marrow under proliferative inflammatory conditions (such as tissue repair). Most importantly, they take on distinct phenotypes and functions crucial to healing upon localization in the wound. The objective of this review is to summarize recent findings in regard to the cellular mechanisms of macrophages and chronic wounds. Advances… CONTINUE READING
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