Macrophage stimulation by bacterial lipopolysaccharides. I. Cytolytic effect on tumor target cells

@article{Doe1978MacrophageSB,
  title={Macrophage stimulation by bacterial lipopolysaccharides. I. Cytolytic effect on tumor target cells},
  author={William F. Doe and Peter M Henson},
  journal={The Journal of Experimental Medicine},
  year={1978},
  volume={148},
  pages={544 - 556}
}
Bacterial lipopolysaccharides (LPS) stimulate mouse peritoneal macrophages to kill tumor cells in vitro. Lysis is confined to tumor cells where it is nonspecific; both allogeneic and syngeneic cells being susceptible. Stimulation by LPS appears to be due to direct interaction between LPS and macrophages and does not involve participation by lymphocytes. After exposure to LPS, a latent period must elapse before macrophages can lyse tumor cells. The cytolytic mechanism requires contact between… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 43 extracted citations

Effects of inflammation products on immune systems

Cancer Immunology, Immunotherapy • 2004
View 2 Excerpts

References

Publications referenced by this paper.
Showing 1-10 of 32 references

Lipopolysaccharide induced macrophage activation

W. F. Doe, D. C. Morrison, P. Henson
1976

Similar Papers

Loading similar papers…