Macrophage-secreted myogenic factors: a promising tool for greatly enhancing the proliferative capacity of myoblasts in vitro and in vivo

@article{Cantini2002MacrophagesecretedMF,
  title={Macrophage-secreted myogenic factors: a promising tool for greatly enhancing the proliferative capacity of myoblasts in vitro and in vivo},
  author={Marcello Cantini and Emanuele Giurisato and Claudia Maria Radu and Stefano Tiozzo and Francesca Pampinella and D. Senigaglia and Giovanna Zaniolo and Federica Mazzoleni and Libero Vitiello},
  journal={Neurological Sciences},
  year={2002},
  volume={23},
  pages={189-194}
}
In this work we set out to determine if the murine macrophage J774 cell line can be used to produce myogenic growth factors. Activated J774 macrophages were grown in serum-free conditions. The macrophage-conditioned medium (MCM) was then used to treat cultures of primary myoblasts and regenerating muscle tissue, in vitro and in vivo respectively. MCM activity in vitro was tested by analyzing the expression of muscle-specific transcription factors, in parallel with the proliferation and… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 15 references

Myo - D positive cells overcome fibroblasts in primary muscle cultures grown in the presence of a 50 - 10 kDa cytokine secreted by macrophages

E Giurisato, L DallaLibera, B Ravara, ML Massimino, M Cantini
Basic Appl Myol • 1998

Partial purification and biochemical characterisation by liquid chromatography of specific myo - mitogenetic factor ( s ) from culture medium of activated macrophages

L DallaLibera, B Martin, ML Massimino, M Cantini
Anal Chim Acta • 1997

The satellite cell and muscle regeneration

R Bischoff
1994