Macrophage migration inhibitory factor (MIF) in bronchial asthma.

  title={Macrophage migration inhibitory factor (MIF) in bronchial asthma.},
  author={Etsuro Yamaguchi and Jun Nishihira and Tadamichi Shimizu and Tomoe Takahashi and N Kitashiro and Nobuyuki Hizawa and Kazuho Kamishima and Yoshikazu Kawakami},
  journal={Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology},
  volume={30 9},
BACKGROUND Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine favouring the secretion of TNFalpha and IL-8 and counteracts anti-inflammatory effects of corticosteroids. Airways inflammation is a central feature of bronchial asthma and is characterized by the accumulation of eosinophils. OBJECTIVE The aim of this study was to investigate whether MIF is related to asthma symptoms and eosinophil accumulation in the airways. METHODS Serum MIF levels were measured by an… CONTINUE READING
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