Macrophage migration inhibitory factor (MIF) expression in human glioblastomas correlates with vascular endothelial growth factor (VEGF) expression.

@article{Munaut2002MacrophageMI,
  title={Macrophage migration inhibitory factor (MIF) expression in human glioblastomas correlates with vascular endothelial growth factor (VEGF) expression.},
  author={Carine Munaut and Jacques Boniver and J. M. Foidart and Manuel Deprez},
  journal={Neuropathology and applied neurobiology},
  year={2002},
  volume={28 6},
  pages={
          452-60
        }
}
Macrophage migration inhibitory factor (MIF) is a peptide released upon hypothalamo-pituitary stimulation that acts as a potent endogenous antagonist of the glucocorticoid inhibition of acute inflammatory response and subsequent antigen-specific response. MIF also sustains tumour growth as it promotes angiogenesis, overcomes p53-mediated cell growth arrest and inhibits tumour-specific immune responses. Using quantitative reverse transcriptase polymerase chain reaction (RT-PCR) and… CONTINUE READING

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