Macrophage metalloelastase (MMP-12) deficiency does not alter bleomycin-induced pulmonary fibrosis in mice

@article{Manoury2005MacrophageM,
  title={Macrophage metalloelastase (MMP-12) deficiency does not alter bleomycin-induced pulmonary fibrosis in mice},
  author={Boris Manoury and Soazig N{\'e}nan and Isabelle Gu{\'e}non and Elisabeth Boichot and J. M. Planquois and Claude P. Bertrand and Vincent Lagente},
  journal={Journal of Inflammation (London, England)},
  year={2005},
  volume={3},
  pages={2 - 2}
}
Pulmonary fibrosis is characterized by excessive deposition of extracellular matrix in the interstitium resulting in respiratory failure. The role of remodeling mediators such as metalloproteinases (MMPs) and their inhibitors (TIMPs) in the fibrogenic process remains misunderstood. In particular, macrophage metalloelastase, also identified as MMP-12, is known to be involved in remodeling processes under pathological conditions. However, MMP-12 involvement in pulmonary fibrosis is unknown. Here… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

MicroRNA-326 regulates profibrotic functions of transforming growth factor-β in pulmonary fibrosis.

American journal of respiratory cell and molecular biology • 2014
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 36 references

Matrix metalloproteinases in lung biology

Respiratory research • 2001
View 13 Excerpts
Highly Influenced

TIMP-1, -2, -3, and -4 in idiopathic pulmonary fibrosis. A prevailing nondegradative lung microenvironment?

American journal of physiology. Lung cellular and molecular physiology • 2000
View 6 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…