Macrophage markers in serum and tumor have prognostic impact in American Joint Committee on Cancer stage I/II melanoma.

@article{Jensen2009MacrophageMI,
  title={Macrophage markers in serum and tumor have prognostic impact in American Joint Committee on Cancer stage I/II melanoma.},
  author={Trine Ollegaard Jensen and Henrik Schmidt and Holger Jon M\oller and Morten H\oyer and Maciej Bogdan Maniecki and Pia Sjoegren and Ib Jarle Christensen and Torben Steiniche},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2009},
  volume={27 20},
  pages={
          3330-7
        }
}
PURPOSE To evaluate the prognostic role of soluble CD163 (sCD163) in serum and macrophage infiltration in primary melanomas from patients with American Joint Committee on Cancer (AJCC) stage I/II melanoma. The scavenger receptor CD163 is associated with anti-inflammatory macrophages, and it is shed from their surface. PATIENTS AND METHODS Serum samples from 227 patients with stage I/II melanoma obtained before definitive surgery (baseline) and during 5 years of follow-up were analyzed for… CONTINUE READING
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