Macrophage infiltration is associated with VEGF and EGFR expression in breast cancer.

@article{Leek2000MacrophageII,
  title={Macrophage infiltration is associated with VEGF and EGFR expression in breast cancer.},
  author={R. Leek and Nicholas C. A. Hunt and Robert J Landers and Claire E. Lewis and J A Royds and Adrian L. Harris},
  journal={The Journal of pathology},
  year={2000},
  volume={190 4},
  pages={430-6}
}
Angiogenesis is esential for tumour growth and metastasis. Vascular endothelial growth factor (VEGF) is a potent endothelial cell mitogen and is an important component of the angiogenic stimulus in a range of human neoplasias. In addition to its mitogenic activities, VEGF has also been found to stimulate migration in macrophages via the flt-1 VEGF receptor. It has previously been shown that increased focal tumour macrophage infiltration is associated with increased angiogenesis and worsened… CONTINUE READING
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