Macrophage form, function, and phenotype in mycobacterial infection: lessons from tuberculosis and other diseases.

Abstract

Macrophages play a central role in mycobacterial pathogenesis. Recent work has highlighted the importance of diverse macrophage types and phenotypes that depend on local environment and developmental origins. In this review, we highlight how distinct macrophage phenotypes may influence disease progression in tuberculosis. In addition, we draw on work… (More)
DOI: 10.1093/femspd/ftw068

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