Macrophage eicosanoid formation is stimulated by platelet arachidonic acid and prostaglandin endoperoxide transfer.

Abstract

The present study was designed to determine whether platelets transfer arachidonic acid or prostaglandin endoperoxide intermediates to macrophages which may be further metabolized into cyclooxygenase products. Adherent peritoneal macrophages were prepared from rats fed either a control diet or an essential fatty acid-deficient diet, and incubated with a… (More)

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@article{Smith1987MacrophageEF, title={Macrophage eicosanoid formation is stimulated by platelet arachidonic acid and prostaglandin endoperoxide transfer.}, author={E. F. Smith and Winnie Wise and Perry V. Halushka and James A. Cook}, journal={Biochimica et biophysica acta}, year={1987}, volume={923 3}, pages={355-61} }