Macrophage distinguishes Vibrio cholerae hemolysin from its protease insensitive oligomer by time dependent and selective expression of CD80-CD86.

@article{Ray2003MacrophageDV,
  title={Macrophage distinguishes Vibrio cholerae hemolysin from its protease insensitive oligomer by time dependent and selective expression of CD80-CD86.},
  author={Avijit Ray and Kausik Chattopadhyay and Kalyan Kumar Banerjee and Tapas Kr. Biswas},
  journal={Immunology letters},
  year={2003},
  volume={89 2-3},
  pages={143-7}
}
The monomeric and oligomeric forms of Vibrio cholerae hemolysin (HlyA), a membrane damaging toxin that forms transmembrane pentameric diffusion channels in target eukaryotic membrane, show a pronounced difference in protease susceptibility, presumably due to masking of sensitive peptide bonds during oligomerization. In this work, we examined if resistance… CONTINUE READING