Macrophage colony-stimulating factor induction of enhanced macrophage anticryptococcal activity: synergy with fluconazole for killing.

Abstract

Enhancement of anticryptococcal activity in macrophages by macrophage colony-stimulating factor (M-CSF) and possible synergy between macrophages and fluconazole for killing of Cryptococcus neoformans were tested. M-CSF (48 h)-treated macrophages underwent dramatic morphologic changes and inhibited cryptococcal multiplication by 96% +/- 4%, which was greater… (More)

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Cite this paper

@article{Brummer1994MacrophageCF, title={Macrophage colony-stimulating factor induction of enhanced macrophage anticryptococcal activity: synergy with fluconazole for killing.}, author={E. Charles Brummer and D. A. Stevens}, journal={The Journal of infectious diseases}, year={1994}, volume={170 1}, pages={173-9} }