Macrophage activation syndrome and reactive hemophagocytic lymphohistiocytosis: the same entities?

  title={Macrophage activation syndrome and reactive hemophagocytic lymphohistiocytosis: the same entities?},
  author={Alexei A. Grom},
  journal={Current opinion in rheumatology},
  volume={15 5},
PURPOSE OF THE REVIEW One of the most perplexing features of systemic-onset juvenile rheumatoid arthritis is the association with macrophage activation syndrome, a life-threatening complication caused by excessive activation and proliferation of T cells and macrophages. The main purpose of the review is to summarize current understanding of the relation between macrophage activation syndrome and other clinically similar hemophagocytic disorders. RECENT FINDINGS Clinically, macrophage… CONTINUE READING
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