Macrophage activation and its role in repair and pathology after spinal cord injury

@article{Gensel2015MacrophageAA,
  title={Macrophage activation and its role in repair and pathology after spinal cord injury},
  author={John C Gensel and Bei Zhang},
  journal={Brain Research},
  year={2015},
  volume={1619},
  pages={1-11}
}
The injured spinal cord does not heal properly. In contrast, tissue repair and functional recovery occur after skin or muscle injuries. The reason for this dichotomy in wound repair is unclear but inflammation, and specifically macrophage activation, likely plays a key role. Macrophages have the ability to promote the repair of injured tissue by regulating transitions through different phase of the healing response. In the current review we compare and contrast the healing and inflammatory… CONTINUE READING
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