Macrophage Scavenger Receptor A Gene Responsive Element in the Promoter of the Human −-Interferon γ Identification of a Print

@inproceedings{Grewal2001MacrophageSR,
  title={Macrophage Scavenger Receptor A Gene Responsive Element in the Promoter of the Human −-Interferon γ Identification of a Print},
  author={Thomas Grewal and Elena Priceputu and Jean Davignon and Lise Bernier},
  year={2001}
}
In the present study, we demonstrate g-interferon (g-IFN)–inducible scavenger receptor A (SR-A) mRNA expression during the early stages of THP-1 and blood monocyte differentiation. Predominant induction of SR-A type II mRNA parallels the increased accumulation of cholesteryl esters under these conditions. A potential signal transducer and activator of transcription (STAT1) binding site ( g-interferon activation site) in the SR-A promoter demonstratesg-IFN–inducible DNA binding activity and is… CONTINUE READING