Macrophage Migration Inhibitory Factor Induces Il-8 Production in Synovial Fibroblasts of Rheumatoid Arthritis

@inproceedings{Minami2002MacrophageMI,
  title={Macrophage Migration Inhibitory Factor Induces Il-8 Production in Synovial Fibroblasts of Rheumatoid Arthritis},
  author={Minami},
  year={2002}
}
INTRODUCTION Rheumatoid arthritis (RA) is an autoimmune disease that is characterized by severe synovitis and cartilage destruction. Synovial cells play a major role in the pathogenesis of RA through the synthesis of various cytokines, proteases, superoxide, etc. Interleukin-8 (IL-8), one of CXC chemokines, is known to recruit neutrophils into inflammatory… CONTINUE READING