Macronuclear Genome Sequence of the Ciliate Tetrahymena thermophila, a Model Eukaryote

@article{Eisen2006MacronuclearGS,
  title={Macronuclear Genome Sequence of the Ciliate Tetrahymena thermophila, a Model Eukaryote},
  author={J. Eisen and R. Coyne and M. Wu and D. Wu and M. Thiagarajan and J. Wortman and J. Badger and Q. Ren and P. Amedeo and K. M. Jones and L. Tallon and A. Delcher and S. Salzberg and J. Silva and B. Haas and William H. Majoros and M. Farzad and J. Carlton and R. Smith and J. Garg and R. Pearlman and K. Karrer and L. Sun and G. Manning and N. Elde and A. Turkewitz and D. Asai and D. E. Wilkes and Y. Wang and H. Cai and K. Collins and B. A. Stewart and S. Lee and K. Wilamowska and Z. Weinberg and W. Ruzzo and D. Wloga and J. Gaertig and J. Frankel and Che-Chia Tsao and M. Gorovsky and P. Keeling and R. Waller and N. Patron and J. Cherry and Nicholas A. Stover and C. Krieger and Christina del Toro and Hilary F Ryder and Sondra C Williamson and Rebecca A Barbeau and E. Hamilton and E. Orias},
  journal={PLoS Biology},
  year={2006},
  volume={4}
}
  • J. Eisen, R. Coyne, +50 authors E. Orias
  • Published 2006
  • Biology, Medicine
  • PLoS Biology
  • The ciliate Tetrahymena thermophila is a model organism for molecular and cellular biology. Like other ciliates, this species has separate germline and soma functions that are embodied by distinct nuclei within a single cell. The germline-like micronucleus (MIC) has its genome held in reserve for sexual reproduction. The soma-like macronucleus (MAC), which possesses a genome processed from that of the MIC, is the center of gene expression and does not directly contribute DNA to sexual progeny… CONTINUE READING
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