Macronuclear DNA demethylation is involved in the encystment process of the ciliate Colpoda inflata.

@article{Palacios1994MacronuclearDD,
  title={Macronuclear DNA demethylation is involved in the encystment process of the ciliate Colpoda inflata.},
  author={Gabriel Fernando Bravo Palacios and Ana Mart{\'i}n-Gonz{\'a}lez and Juan Carlos Guti{\'e}rrez},
  journal={Cell biology international},
  year={1994},
  volume={18 4},
  pages={223-8}
}
Ciliate encystment is an eukaryotic cell differentiation process which involves a specific gene expression, to form the resting stage. In this study, we investigate, for first time, the DNA methylation pattern changes during encystment in the ciliate Colpoda inflata, and the 5-azacytidine effect on growing cells and encystment. Results indicate that 5-methylcytosine is present in macronuclear DNA of this ciliate and the 5-azacytidine treatment induces encystment in growth conditions. From… CONTINUE READING