Macromolecules and urolithiasis: parallels and paradoxes.

  title={Macromolecules and urolithiasis: parallels and paradoxes.},
  author={Rosemary Lyons Ryall},
  journal={Nephron. Physiology},
  volume={98 2},
Long-standing interest in the possible role of macromolecules in urolithiasis stems from the observation that all human kidney stones consist of a complex amalgam of mineral and organic material. This review summarises what is currently known or is hypothesised about the influences of urinary macromolecules, especially proteins, on the formation of calcium oxalate crystals, their attachment to renal epithelial cells, and their subsequent destruction within those cells. Although a list is… CONTINUE READING