author={Charles Tanford},
  journal={Protein Science},
  • C. Tanford
  • Published 1 May 1994
  • Medicine
  • Protein Science
1 Learning Outcomes: Macromolecules • List and describe the four major classes of molecules • Describe the formation of a glycosidic linkage and distinguish between monosaccharides, disaccharides, and polysaccharides • Distinguish between saturated and unsaturated fats and between cis and trans fat molecules • Describe the four levels of protein structure • Distinguish between the following pairs: pyrimidine and purine, nucleotide and nucleoside, ribose and deoxyribose, the 5′ end and 3′ end of… Expand
Synthesis and applications of end-labeled neoglycopolymers.
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RAFT polymers for protein recognition
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Liquid Crystalline Behavior Of Two-Component Molecular Adducts From Bifunctional Molecules-II
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The complete derivatization of amine groups (lysine side chains and N-termini) on three different proteins are demonstrated by addition of activated carboxylate reagents in aqueous solutions containing sodium dedecyl sulfate (SDS), under denaturing conditions. Expand
Microsecond kinetics in model single- and double-stranded amylose polymers† †Electronic supplementary information (ESI) available: Detailed structural definitions, methodological descriptions, analyses of the simulations and computed and experimental molecular properties are provided. See DOI: 10.10
Amylose, a component of starch with increasing biotechnological significance, is a linear glucose polysaccharide that self-organizes into single- and double-helical assemblies.
Interpenetrated molecules: crown-ether and linear organic molecule supramolecular architectures
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New approaches to the investigation of hyaluronan networks.
The tetrasaccharides populate a relatively small number of defined conformations and the hyaluronan exchanges between all of its hydrogen bonds thousands of times within a microsecond, indicating the validity of the approach. Expand
n→π* interactions in poly(lactic acid) suggest a role in protein folding.
It is concluded that analogous n→π* interactions could direct the folding of a polypeptide chain into a polyproline II helix prior to the formation of hydrogen bonds between backbone amides. Expand
Carboxylated Glucuronic Poly-amido-saccharides as Protein Stabilizing Agents
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From small building blocks to complex molecular architecture.
A modular approach based on stepwise protection chemistry starting from simple building blocks is employed, which makes it applicable for linear monofunctionalized precursors of any kind and allows for precise control of the number of arms. Expand