Macromolecular adducts and related biomarkers in biomonitoring and epidemiology of complex exposures.

Abstract

In order to evaluate the potential of biological markers in epidemiology and risk assessment of complex exposures, we review recent studies of macromolecular adducts and oncogene activation in human populations. Results are discussed in terms of the strengths and weaknesses of various study designs in order to identify the most promising approaches for… (More)

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