Macrolides: from in vitro anti-inflammatory and immunomodulatory properties to clinical practice in respiratory diseases

@article{Zarogoulidis2012MacrolidesFI,
  title={Macrolides: from in vitro anti-inflammatory and immunomodulatory properties to clinical practice in respiratory diseases},
  author={Paul Zarogoulidis and Nikolaos Papanas and Ioannis P. Kioumis and Ekaterini Chatzaki and Efstratios S Maltezos and Konstantinos Zarogoulidis},
  journal={European Journal of Clinical Pharmacology},
  year={2012},
  volume={68},
  pages={479-503}
}
BackgroundMacrolides have long been recognised to exert immunomodulary and anti-inflammatory actions. They are able to suppress the “cytokine storm” of inflammation and to confer an additional clinical benefit through their immunomodulatory properties.MethodsA search of electronic journal articles was performed using combinations of the following keywords: macrolides, COPD, asthma, bronchitis, bronchiolitis obliterans, cystic fibrosis, immunomodulation, anti-inflammatory effect, diabetes, side… 

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