Macrolide prescriptions and erythromycin resistance of Streptococcus pyogenes.

@article{Gagliotti2006MacrolidePA,
  title={Macrolide prescriptions and erythromycin resistance of Streptococcus pyogenes.},
  author={Carlo Gagliotti and Lucia Nobilio and Milena Milandri and Maria Luisa Moro},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2006},
  volume={42 8},
  pages={1153-6}
}
This study shows a significant association between the number of macrolide prescriptions reimbursed by the Italian National Health Service and resistance of Streptococcus pyogenes to erythromycin in children from a region in northern Italy with high prevalence of erythromycin resistance. Recent prescription of a macrolide (especially azithromycin) is a predictor of erythromycin resistance, as well as a possible risk factor for resistance at a community level.