Macrolide antibiotics as biological response modifiers.


Erythromycin was first isolated in the 1950s from a Philippine soil sample, and the derivatives of erythromycin A, called the macrolide antibiotics, have been used as effective antibacterial agents ever since. It has long been suspected that the 14-membered macrolides have immunomodulatory activity as demonstrated by their early use as adjunctive therapy… (More)


Cite this paper

@article{Rubin2000MacrolideAA, title={Macrolide antibiotics as biological response modifiers.}, author={Bruce K. Rubin and Junya Tamaoki}, journal={Current opinion in investigational drugs}, year={2000}, volume={1 2}, pages={169-72} }