Macrochimerism in Intestinal Transplantation: Association With Lower Rejection Rates and Multivisceral Transplants, Without GVHD.

@article{Zuber2015MacrochimerismII,
  title={Macrochimerism in Intestinal Transplantation: Association With Lower Rejection Rates and Multivisceral Transplants, Without GVHD.},
  author={Julien Zuber and Sarah J. Rosen and Brittany A. Shonts and Ben Sprangers and Talicia Savage and Sherif Richman and Suxiao R Yang and S P Lau and Susan DeWolf and Donna L Farber and George Vlad and Emmanuel Zorn and W. Douglas Wong and J. C. Emond and Bruce Levin and M Ronchas Martinez and Tomoaki Kato and Megan Sykes},
  journal={American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons},
  year={2015},
  volume={15 10},
  pages={2691-703}
}
Blood chimerism has been reported sporadically among visceral transplant recipients, mostly in association with graft-vs-host disease (GVHD). We hypothesized that a higher degree of mixed chimerism would be observed in multivisceral (MVTx) than in isolated intestinal (iITx) and isolated liver transplant (iLTx) recipients, regardless of GVHD. We performed a longitudinal prospective study investigating multilineage blood chimerism with flow cytometry in 5 iITx and 4 MVTx recipients up to one year… CONTINUE READING