Machine perfusion or cold storage in deceased-donor kidney transplantation.

  title={Machine perfusion or cold storage in deceased-donor kidney transplantation.},
  author={Cyril Moers and Jacqueline M. Smits and Mark-Hugo J. Maathuis and J{\"u}rgen W Treckmann and Frank van Gelder and Bogdan P. Napieralski and Margitta van Kasterop-Kutz and Jaap J. Homan van der Heide and Jean Paul Squifflet and Ernest van Heurn and Gunter Kirste and Axel Rahmel and Henri G. D. Leuvenink and Andreas Paul and Jacques Pirenne and Rutger J. Ploeg},
  journal={The New England journal of medicine},
  volume={360 1},
BACKGROUND Static cold storage is generally used to preserve kidney allografts from deceased donors. Hypothermic machine perfusion may improve outcomes after transplantation, but few sufficiently powered prospective studies have addressed this possibility. METHODS In this international randomized, controlled trial, we randomly assigned one kidney from 336 consecutive deceased donors to machine perfusion and the other to cold storage. All 672 recipients were followed for 1 year. The primary… 

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