Machine Learning for Deep Brain Stimulation Efficacy using Dense Array EEG

@article{Stuart2019MachineLF,
  title={Machine Learning for Deep Brain Stimulation Efficacy using Dense Array EEG},
  author={Morgan Stuart and Chathurika S. Wickramasinghe and Daniel L. Marino and Deepak Kumbhare and Kathryn L. Holloway and Milos Manic},
  journal={2019 12th International Conference on Human System Interaction (HSI)},
  year={2019},
  pages={143-150}
}
Deep brain stimulation (DBS) is well recognized as an effective treatment for symptoms of movement disorders such as Parkinson's disease (PD), Essential Tremor, and dystonia. The selection of the appropriate contact on the DBS lead for optimal clinical efficacy can be challenging, particularly when considering directional leads. Electroencephalograms (EEG) and electrocorticography has been utilized to better understand the pathophysiology of PD but a methodology to provide an objective… 
Machine Learning’s Application in Deep Brain Stimulation for Parkinson’s Disease: A Review
TLDR
A comprehensive review of the literature from PubMed, the Institute for Scientific Information’s Web of Science, Cochrane Database of Systematic Reviews, and Institute of Electrical and Electronics Engineers’ (IEEE) Xplore Digital Library for ML applications in DBS is performed.

References

SHOWING 1-10 OF 42 REFERENCES
Deep Brain Stimulation Programming for Movement Disorders: Current Concepts and Evidence-Based Strategies
TLDR
An evidence-based strategy for achieving the best clinical effect with different disorders and avoiding adverse effects in DBS of the subthalamic nucleus, the ventro-intermedius nucleus (VIM), and the globus pallidus internus (GPi) is provided.
Therapeutic deep brain stimulation reduces cortical phase-amplitude coupling in Parkinson's disease
TLDR
It is proposed that DBS of the basal ganglia improves cortical function by alleviating excessive beta phase locking of motor cortex neurons.
Cortical Potentials Evoked by Deep Brain Stimulation in the Subthalamic Area
TLDR
This review surveys the literature from recording studies in human patients treated with STN–DBS for Parkinson's disease and other conditions, as well as recent animal studies that have begun to elucidate details of the pathways, frequency dependencies, and other features of EPs.
Elevated synchrony in Parkinson disease detected with electroencephalography
TLDR
Whether beta‐gamma PAC over sensorimotor cortex, recorded noninvasively with EEG, differs between PD patients off and on medications, and healthy control subjects is tested.
The safety and efficacy of thalamic deep brain stimulation in essential tremor: 10 years and beyond
TLDR
Thalamic DBS is a safe and effective therapy in patients with essential tremor followed for up to 13 years, and a total non-blinded improvement in the tremor rating scale of 39% was observed in the ‘on’ state.
Thalamic Deep Brain Stimulation for Essential Tremor: Relation of Lead Location to Outcome
TLDR
Optimal electrode location for thalamic DBS in essential tremor corresponds to the anterior margin of the ventralis intermedius nucleus, and leads located greater than 2 mm from the optimal coordinates are more likely to be associated with poor tremor control.
Deep Brain Stimulation for Treatment of Tremor.
A comparison of continuous thalamic stimulation and thalamotomy for suppression of severe tremor.
TLDR
Thalamic stimulation and thalamotomy are equally effective for the suppression of drug-resistant tremor, but thalamicstimulation has fewer adverse effects and results in a greater improvement in function.
Pallidal Deep-Brain Stimulation Disrupts Pallidal Beta Oscillations and Coherence with Primary Motor Cortex in Parkinson's Disease
TLDR
The results support the hypothesis that specific motor phenomenology observed in movement Disorders are associated with elevated network oscillations in specific frequency bands, and that DBS in movement disorders acts in general by disrupting elevated synchronization between basal ganglia output and motor cortex.
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