Machine‐Learning Techniques Applied to Antibacterial Drug Discovery

  title={Machine‐Learning Techniques Applied to Antibacterial Drug Discovery},
  author={Jacob D. Durrant and Rommie E. Amaro},
  journal={Chemical Biology \& Drug Design},
The emergence of drug‐resistant bacteria threatens to revert humanity back to the preantibiotic era. Even now, multidrug‐resistant bacterial infections annually result in millions of hospital days, billions in healthcare costs, and, most importantly, tens of thousands of lives lost. As many pharmaceutical companies have abandoned antibiotic development in search of more lucrative therapeutics, academic researchers are uniquely positioned to fill the pipeline. Traditional high‐throughput screens… 

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