Macaque sperm coating protein DEFB126 facilitates sperm penetration of cervical mucus.

Abstract

BACKGROUND Sperm coating protein beta-defensin 126 (DEFB126) is adsorbed onto the entire surface of macaque sperm in the caudal epididymis and is retained on viable sperm collected from the cervix and the uterine lumen of mated female macaques. We investigated the role of sperm coating protein DEFB126 in cervical mucus penetration (CMP). METHODS Cervical… (More)
DOI: 10.1093/humrep/den276

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