Macagigantin, a farnesylated flavonol from Macaranga gigantea

@article{Tanjung2009MacagigantinAF,
  title={Macagigantin, a farnesylated flavonol from Macaranga gigantea},
  author={Mulyadi Tanjung and Euis Holisotan Hakim and Didin Mujahidin and Muhammad Hanafi and Yana M. Syah},
  journal={Journal of Asian Natural Products Research},
  year={2009},
  volume={11},
  pages={929 - 932}
}
A new farnesylated flavonol derivative, macagigantin (1), together with two known flavonoids, glyasperin A (2) and apigenin (3), had been isolated from the acetone extract of the leaves of Macaranga gigantea. The structure of the new compound was elucidated as 6-farnesylkaempferol based on its spectroscopic data, including UV, IR, 1D and 2D NMR, and HR-EI-MS spectra. Compounds 1–3 were evaluated for their cytotoxic properties against P-388 cells, their IC50 values being 11.3, 6.0, and 5.1 μM… 

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ounds on the Article history: Received 26 January 2015 2015 ⁎ Corresponding authors. Tel.:/fax: +86 871 E-mail addresses: li_xiaoli11@mail.kib.ac.cn (W.-L. Xiao). 1 These authors contributed equally

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