Corpus ID: 74143949

MYALGIC ENCEPHALOMYELITIS - Adult & Paediatric: International Consensus Primer for Medical Practitioners

@inproceedings{Meirleir2012MYALGICE,
  title={MYALGIC ENCEPHALOMYELITIS - Adult \& Paediatric: International Consensus Primer for Medical Practitioners},
  author={Kenny L. De Meirleir and Lucinda Bateman and Austin Darragh and Bruce M. Carruthers},
  year={2012}
}
clinician: internal medicine-pathophysiology and haematology Retired clinical haematologist with 28 years of experience of ME and chronic fatigue syndrome, Suffolk, UK Retired clinical paediatrician with many years of experience of ME and chronic fatigue syndrome. Authors and their affiliations are continued on the back inside cover. This primer is a not-for-profit educational document. In our efforts to enhance the understanding of ME and promote international consistency in optimal clinical… Expand
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TLDR
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References

SHOWING 1-10 OF 206 REFERENCES
Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols
TLDR
A systematic clinical working case definition for myalgic encephalomyelitis is presented and an Ex- pert Medical Consensus Panel representing treating physicians, teaching faculty and researchers are selected. Expand
Immunological aspects of chronic fatigue syndrome.
TLDR
The immunological aspects of CFS are discussed and an immunological hypothesis for the disease processes is offered and may explain some of the manifestations such as fatigue and flu-like symptoms and influence NK activity. Expand
Postexertional malaise in women with chronic fatigue syndrome.
TLDR
The results of this study suggest that PEM is both a real and an incapacitating condition for women with CFS and that their responses to exercise are distinctively different from those of sedentary controls. Expand
A chronic illness characterized by fatigue, neurologic and immunologic disorders, and active human herpesvirus type 6 infection.
OBJECTIVE To conduct neurologic, immunologic, and virologic studies in patients with a chronic debilitating illness of acute onset. DESIGN Cohort study with comparison to matched, healthy controlExpand
Mitochondrial dysfunction and the pathophysiology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).
TLDR
It is found that all patients tested have measureable mitochondrial dysfunction which correlates with the severity of the illness, and the ATP Profile is a valuable diagnostic tool for the clinical management of ME/CFS. Expand
The role of enterovirus in chronic fatigue syndrome
  • J. Chia
  • Medicine
  • Journal of Clinical Pathology
  • 2005
TLDR
The available experimental and clinical evidence that supports the role of enterovirus in chronic fatigue syndrome is summarized. Expand
Comparing the Fukuda et al. Criteria and the Canadian Case Definition for Chronic Fatigue Syndrome
TLDR
Differences between CFS as defined by Fukuda et al. (1994) and a set of criteria that has been proposed for a clinical Canadian Case definition are examined. Expand
Immunological abnormalities as potential biomarkers in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis
TLDR
Investigating the profile of markers of immune function in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis patients found immunological abnormalities which may serve as biomarkers in CFS/ME patients with potential for an application as a diagnostic tool. Expand
Post-infective and chronic fatigue syndromes precipitated by viral and non-viral pathogens: prospective cohort study
TLDR
Post-infective fatigue syndrome is a valid illness model for investigating one pathophysiological pathway to chronic fatigue syndrome and persists in a significant minority of patients for six months or more after clinical infection with several different viral and non-viral micro-organisms. Expand
Illness from low levels of environmental chemicals: relevance to chronic fatigue syndrome and fibromyalgia.
TLDR
The ability of multiple types of widely divergent stimuli to initiate and elicit sensitization offers a new perspective on the search for mechanisms of illness in CFS and fibromyalgia with CI. Expand
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