MX homologous protein in mononuclear cells from patients with systemic lupus erythematosus.

@article{Wussow1989MXHP,
  title={MX homologous protein in mononuclear cells from patients with systemic lupus erythematosus.},
  author={Peter von Wussow and D. Jakschies and H. K. Hochkeppel and Michel Andr{\'e} Horisberger and Klaus Hartung and Helmuth R. G. Deicher},
  journal={Arthritis and rheumatism},
  year={1989},
  volume={32 7},
  pages={914-8}
}
The 76-kd human interferon (IFN)-induced MX protein is the homolog to the murine protein, which is necessary and sufficient to provide adequate resistance to influenza virus infection in murine cells and in mice. Fifty-one patients with systemic lupus erythematosus (SLE) were screened for the presence of the MX homolog in mononuclear cells and for IFN and anti-IFN antibodies in serum. In 47 of 51 patients, significant levels of the MX homolog were found, while only 15 of 51 patients had… CONTINUE READING

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