MUTYH gene variants and breast cancer in a Dutch case–control study

@inproceedings{Out2012MUTYHGV,
  title={MUTYH gene variants and breast cancer in a Dutch case–control study},
  author={Astrid A. Out and Marijke Wasielewski and Petra E. A. Huijts and Ivonne J. H. M. van Minderhout and Jeanine J. Houwing-Duistermaat and Carli M. J. Tops and Maartje Nielsen and Caroline M. Seynaeve and Juul Th Wijnen and Martijn H. Breuning and Christi J. van Asperen and Mieke Schutte and Frederik J Hes and Peter Devilee},
  booktitle={Breast Cancer Research and Treatment},
  year={2012}
}
The MUTYH gene is involved in base excision repair. MUTYH mutations predispose to recessively inherited colorectal polyposis and cancer. Here, we evaluate an association with breast cancer (BC), following up our previous finding of an elevated BC frequency among Dutch bi-allelic MUTYH mutation carriers. A case–control study was performed comparing 1,469… CONTINUE READING