MUC5B Is the Predominant Mucin Glycoprotein in Chronic Otitis Media Fluid

@article{Preciado2010MUC5BIT,
  title={MUC5B Is the Predominant Mucin Glycoprotein in Chronic Otitis Media Fluid},
  author={Diego Preciado and Samita Goyal and Michael Rahimi and Alan M. Watson and Kristy Jean Brown and Yetrib Hathout and Mary Carman Rose},
  journal={Pediatric Research},
  year={2010},
  volume={68},
  pages={231-236}
}
Chronic otitis media (COM), e.g. “glue” ear is characterized by middle ear effusion and conductive hearing loss. Although mucous glycoproteins (mucins), which contribute to increased effusion viscosity, have been analyzed in ear tissue specimens, no studies have been reported that characterize the molecular identity of secreted mucin proteins present in actual middle ear fluid. For this study, effusions from children with COM undergoing myringotomy at Children's National Medical Center… CONTINUE READING